Serum amphotericin B concentration in a very premature infant with disseminated candidiasis.

Obstructive renal candidiasis in a premature infant

Pharmacodynamics of amphotericin B in a neutropenic-mouse disseminated-candidiasis model.

In vivo pharmacodynamic parameters have been described for a variety of antibacterials. These parameters have been studied in correlation with in vivo outcomes in order to determine which dosing parameter is predictive of outcome and the magnitude of that parameter associated with efficacy. Very little is known about pharmacodynamics for antifungal agents. We utilized a neutropenic mouse model ...

Disseminated histoplasmosis successfully treated with amphotericin B.

A 61-year-old woman presented with malaise, intermittent fever, weight loss, and epigastric pain. Histoplasma capsulatum was eventually isolated from a liver biopsy and from the bone marrow and the patient was successfully treated with amphotericin B.

Successful Management of an Extremely Premature Infant with Congenital Candidiasis

Congenital candidiasis, which presents with a variety of clinical symptoms, is very rare in both term and preterm infants, and less than 100 neonatal cases have been reported in the medical literature. We describe the case of an extremely premature infant with congenital candidiasis, who was successfully treated and survived without major sequelae. A male infant was born at 25 weeks' gestation ...

Disseminated histoplasmosis treated with amphotericin B. Report of a case.